Scientist I/Scientist II, Medicinal Chemistry

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At DICE Therapeutics, we design and develop innovative therapies in immunology for patients with debilitating disease. Seeking to create a future where convenient oral medicines with biologic-like efficacy are available to patients with serious medical conditions, we are developing oral alternatives to medicines currently limited to injectable forms.

Essential Functions:

We seek an exceptional Scientist I/Scientist II to join our medicinal chemistry team. This individual will be a key contributor to the design and synthesis of molecules to support ongoing and new research programs. Must have legal right to work in US.

Key Responsibilities:

  • Small molecule drug design based on medicinal chemistry principles (SAR, SPR, MPO and approaches using data from IVP and DMPK)
  • Continuous development of strong medicinal chemistry principles
  • Synthetic route design and optimization in support of internal and external chemists
  • Management of external synthetic chemistry FTE’s
  • Cross-functional collaboration with colleagues in pharmacology, DMPK, and computational chemistry to achieve program goals

Preferred Experience and Education:

  • PhD in organic or medicinal chemistry + 0-3 yrs or MS + 5-8 yrs industrial experience

Preferred Additional Skills:

  • Independent medicinal chemist with experience working as part of a cross collaborative team
  • Track record of contributions in Hit ID, Hit to Lead, and/or Lead Optimization
  • Expert knowledge of synthetic chemistry literature
  • Strong organizational and time-management skills
  • Excellent written and oral communication skills
  • Team player; comfortable and effective in a cross-collaborative research environment


The above information on this description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities, and qualifications required of employees assigned to this job.

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